pyruvate dehydrogenase - traducción al árabe
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pyruvate dehydrogenase - traducción al árabe

CLASS OF ENZYMES
Pyruvate dehydrogenase (lipoamide); Link reaction; The link reaction; Pyruvate dehydrogenase reaction; Transition reaction; PDH complex; Pyruvate dehydrogenase (acetyl-transferring); Oxydative decarboxylation; EC 1.2.4.1; Pyruvate:(dihydrolipoyllysine-residue acetyltransferase)-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
  • left
  • Simplified mechanism for pyruvate dehydrogenase reaction. The TPP coenzyme is shown with abbreviated substituents.
  • 350px
  • Pyruvate dehydrogenase E1 subunit of ''E. coli''.  Colors represent different chains.  Structure determined by Arjunan et al. ''Biochemistry'' 2002.  Created with PyMol.

pyruvate dehydrogenase         
‎ نازِعَةُ هيدروجين البَيرُوفات‎
lactic dehydrogenase         
  • 400px
  • Arrow pushing mechanism for the reaction catalyzed by lactate dehydrogenase
  • Reaction catalyzed by lactate dehydrogenase
‎ نازِعَةُ هيدروجينِ اللَّاكْتات‎
lactate dehydrogenase         
  • 400px
  • Arrow pushing mechanism for the reaction catalyzed by lactate dehydrogenase
  • Reaction catalyzed by lactate dehydrogenase
‎ نازِعَةُ هيدروجينِ اللَّاكْتات‎

Definición

pyruvate
[p??'ru:ve?t]
¦ noun Biochemistry a salt or ester of pyruvic acid.

Wikipedia

Pyruvate dehydrogenase

Pyruvate dehydrogenase is an enzyme that catalyzes the reaction of pyruvate and a lipoamide to give the acetylated dihydrolipoamide and carbon dioxide. The conversion requires the coenzyme thiamine pyrophosphate.

Pyruvate dehydrogenase is usually encountered as a component, referred to as E1, of the pyruvate dehydrogenase complex (PDC). PDC consists of other enzymes, referred to as E2 and E3. Collectively E1-E3 transform pyruvate, NAD+, coenzyme A into acetyl-CoA, CO2, and NADH. The conversion is crucial because acetyl-CoA may then be used in the citric acid cycle to carry out cellular respiration. To distinguish between this enzyme and the PDC, it is systematically called pyruvate dehydrogenase (acetyl-transferring).